Ungatshaya imbiza eqhelekileyo kwaye ube neegummies ze-CBD. Iyakwenza isiphumo esibizwa ngokuba 'yiEntourage Effect', esonyusa izibonelelo ze-CBD gummies.
I-CBD (i-cannabidiol) kunye ne-THC (i-tetrahydrocannabinol) zimbini zezona zininzi kakhulu ze-cannabinoids ezivela kwizityalo ze-cannabis. Ziveliswa ngezixa ezilinganayo nge-cannabis kunye ne-hemp. I-Cannabis, kwelinye icala, inepesenti enkulu ye-THC ngelixa i-Hemp inepesenti enkulu ye-CBD kunentsangu.I-CBD kunye ne-THC zinenani elifanayo le-athomu ye-carbon, i-athomu ye-hydrogen engamashumi amathathu, kunye ne-oxygen ezimbini. Ukwahlula kungenxa yokuba abanalo ulwakhiwo lweekhemikhali ezifanayo kwaye ke ngoko bafunxwa ngumzimba njengeamolekyuli ezahlukeneyo. Ezi khemikhali zisebenzisana ne-neurotransmitters kwingqondo kwaye zichaphazela isimo sengqondo, intlungu, ukulala kunye nenkumbulo.
Kulo lonke inqaku, siza kuthathela ingqalelo iigummies ze-CBD njenge-CBD kunye nembiza eqhelekileyo okanye intsangu (i-cannabis) njenge-THC, kuba yeyona nto iphambili. Nangona zombini i-CBD kunye ne-THC ziphuma kwi-cannabis, zombini zahluke kakhulu. Ngoku, makhe sifunde ngakumbi malunga ne-CBD kunye ne-THC.
Yintoni i-CBD?
I-CBD yikhemikhali yendalo efumaneka kwintyatyambo enentlaka ye-cannabis, isityalo esinembali ende njengeyeza eliyeza elisukela kumawaka eminyaka eyadlulayo. Namhlanje, izazinzulu kunye noogqirha kwihlabathi liphela bayavavanya kwaye baqinisekisa izibonelelo zonyango ze-CBD. Iyikhemikhali engeyiyo i-addictive kunye ne-non-toxic engaphezu kwekhulu "i-phytocannabinoids" efumaneka kuphela kwi-cannabis, inika isityalo ngeprofayili yamayeza anamandla.
I-CBD idityaniswe ngokusondeleyo nenye i-phytocannabinoid ebalulekileyo esebenzayo kwezamayeza: i-THC, icandelo le-psychoactive ye-cannabis. La ngamacandelo amabini e-cannabis ebengumxholo wophando olukhulu lwesayensi. I-CBD kunye ne-THC zombini zineempawu zonyango ezininzi. Nangona kunjalo, ngokungafaniyo ne-THC, i-CBD ayibangeli ukozela okanye ukunxila. Kungenxa yokuba i-CBD kunye ne-THC zisebenza ngokwahlukileyo kwingqondo kunye nezinye ii-receptors ezahlukeneyo.
I-CBD inokunciphisa okanye iphelise iziphumo ezinxilisayo ze-THC, kuxhomekeke kwisixa esithathiweyo. Abantu abaninzi bafuna izibonelelo zempilo ze-cannabis ngaphandle kokufumana "phezulu" - okanye ubuncinci inqanaba lokunxila. I-CBD yamandla amayeza, indalo enganxilisiyo, kunye nokulula kolawulo njengeoli ye-CBD yenza kube yinto ekhangayo yonyango olukhethiweyo kubantu abathandabuzayo ukuzama i-cannabis okokuqala.
Yintoni iTHC?
I-THC, eyaziwa njenge-tetrahydrocannabinol, sisithako se-psychoactive kwi-cannabis esenza ukuba uzive "uphezulu." Ifumaneka kwintsangu kunye ne-hemp.Kwelinye icala, iTHC inesakhiwo esifana neso sekhemikhali yendalo ye-anandamide (eveliswa kwingqondo), itshintsha umsebenzi wonxibelelwano. Ngenxa yoku, kunokuba unxibelelwano lwengqondo oluqhelekileyo lwenzeka ngee-neuron, i-molecule ye-THC inamathela kwi-neurons kwaye iguqule inkqubo.
Ngokutsho kweNational Institute on Drug Abuse (NIDA), kuye kwaboniswa ukuba iTHC ichaphazela izinto ezifana nokucubungula ingcinga, inkumbulo, ukonwaba, ukuhoywa, ukulungelelaniswa, kunye nombono weemvakalelo kunye nokwexeshana. Ngezi zizathu, ukuzibandakanya kwimisebenzi efana nokusebenzisa izixhobo ezinzima okanye ukuqhuba ngelixa uphantsi kweempembelelo zeTHC kunokuba yingozi.
Nangona kunjalo, unxibelelwano olubi olunxulunyaniswa ne-THC (ingakumbi ngokunxulumene nokusetyenziswa kwentsangu) lusenokungameli umfanekiso opheleleyo. Umzekelo, i-THC ibonakaliswe ukuba ibonelela ngezibonelelo ezininzi zempilo, kubandakanya ukunyanga uxinzelelo, ukuphazamiseka kwengqondo emva kokwenzakala (PTSD), ukuxhuzula, kunye neengxaki zokutya.
Ngaba ungayisebenzisa i-CBD kwaye wenze iPot?
Ngokwenyani ungatya i-cannabis (yenza imbiza) ngelixa usebenzisa CBD gummies . Iyakudala isiphumo esibizwa ngokuba yi "Entourage Effect."
I-Entourage Effect iyenzeka xa i-CBD idityaniswa ne-THC (kubandakanywa nezinye i-cannabinoids kunye ne-phytosterols). Oku kuthetha ukuba iikhemikhali zisebenza ngokubambisana kwaye zinamandla ngakumbi xa zidityanisiwe kunaxa zisetyenziswa zodwa.
I-CBD inokuchasana nenxalenye ye-THC's trait ye-psychoactive, nto leyo ethetha ukuba ukuphakama kuya kuba ngaphantsi, ukulinganisela, kunye nempilo. I-CBD ikwasisithinteli sokutya, esinokukunceda ukunqanda ukutyiwa ukuba kuyingxaki. Masikhe sazi ngakumbi malunga nesiphumo se-Entourage.
Entourage Effect
Lo ngumbono wokuba zonke iikhemikhali ezikwi-cannabis zisebenza ngokuhambelana. Ke ngoko, xa isetyenziswe ngokudibeneyo, isiphumo esinamandla ngakumbi siyadalwa kunesimbuku sabo ngasinye.
Izibonelelo zonyango zamacandelo ahlukeneyo e-cannabis zinokutshintshwa okanye zonyuswe xa zidityanisiwe kwifomu enye. Ukongeza, incasa kunye nesakhono se-psychoactive sempahla sinokuguqulwa, okukhokelela kwiimveliso ezahlukeneyo ezineempawu ezahlukeneyo.
Ngokwabaxhasi bayo, impembelelo yeqela eliguquguqukayo inokubonelela ngeempawu ezivelayo, ezinje ngokuphumla kweentlungu, ebezingayi kufumaneka kwi-THC ecocekileyo okanye kwi-CBD.
Abantu abaninzi abasebenza ngokusondeleyo ne-cannabis bacinga ukuba impembelelo ye-entourage inokuphucula kakhulu ukusetyenziswa kwezonyango kwe-THC kunye ne-CBD, nokuba ngokwandisa iziphumo zabo esele zisaziwa okanye ngokwandisa uluhlu lwabo lonyango olunokubakho.
Ukukwazi kweekhemikhali ze-cannabis ukuncamathela kwi-endocannabinoid receptors esele ikhona kwingqondo kwaye kuyo yonke inkqubo ye-nervous central inoxanduva lwezibonelelo zonyango. Nangona inkqubo ye-endocannabinoid yomntu yenzelwe ukunxibelelana ne-endogenous cannabinoids eveliswa ngumzimba, iikhemikhali ezifunyenwe kwizityalo ze-cannabis nazo zinokubophelela ezi zamkeli.
Xa sithatha i-cannabis yonyango ekumgangatho ophezulu, izibonelelo zempilo zininzi. Impembelelo ye-entourage inokuba yenye yezinto ezinegalelo ekusebenzeni kwentsangu njengonyango.
I-Phytocannabinoids zikhompawundi ezifumaneka kwizityalo ze-cannabis ezinenani elingaphezulu kwe-120 yeentlobo ezahlukeneyo. Ezi phytocannabinoids zichaphazela inkqubo ye-endocannabinoid, ejongene nokugcina ibhalansi emzimbeni wakho.
Njengoko sele kukhankanyiwe, ezinye iiphononongo zibonisa ukuba ukuthatha i-CBD kunye ne-THC kunye (kunye nezinye izinto ezincinci zekhemikhali ezifumaneka kwisityalo se-cannabis esaziwa ngokuba yi-terpenes okanye i-terpenoids) kunokuba luncedo kunokuba uzithathe ngokwahlukeneyo.
Ingaba i-Entourage Effect ivakalelwa njani?
I-CBD isebenzisana ne-CB1 kunye ne-CB2 i-receptors kodwa ayibopheleli nakweyiphi na yala ma-receptors. Oku kuqhelekile phakathi kwe-cannabinoids, njengoko uza kubona ngezantsi. Ngeoyile ye-CBD egcweleyo okanye ebanzi, ungenisa uluhlu olwahlukeneyo lwe-cannabinoids ezibophelela kwi-receptors kwinkqubo ye-nervous kunye ne-peripheral nervous system, okukhokelela kwiinzuzo ezahlukeneyo zempilo. Impembelelo ye-entourage inokucingelwa njengokwandiswa kwenkqubo yakho ye-endocannabinoid eyenzeka ngenxa yokusetyenziswa kwee-cannabinoids ezininzi.Ukuba uthenga iigummies ze-CBD, uya kufumanisa ukuba zibandakanya uluhlu olwahlukileyo lwe-cannabinoids kune-CBD nje. Oku akwenzekanga nje ngamabona-ndenzile kodwa kwenziwa ngobukrelekrele.
Uphando ukuza kuthi ga ngoku lufumene iimeko ezithile ezinceda abasebenzisi kakhulu kwindibaniselwano ye-CBD, iTHC, kunye nezinye i-terpenes. Umzekelo, ngokutsho kophononongo olupapashwe kwi Ijenali yaseBritane yePharmacology , indibaniselwano echanekileyo inokunceda iintlungu, ukuxhuzula, ixhala, ukosulelwa ngumngundo, kwanezinye iintlobo zomhlaza.
Ingqalelo eyongezelelweyo kufuneka inikwe kwinto yokuba i-CBD inokunciphisa iziphumo ze-psychoactive ze-THC.
Izibonelelo ze-CBD Gummies
I-CBD iluncedo kwi unyango lweentlungu , ixhala, ukudakumba, kunye nokudumba I-oyile ye-CBD efakwe kwi-gummies inokunceda kakhulu ukuphazamiseka kokulala . I-FDA igunyaze ukusetyenziswa kweyeza le-CBD (Epidiolex) ukunyanga isifo sokuxhuzula.
I-CBD gummies inokuba luncedo kunyango lwexhala, uxinzelelo kunye neentlungu. Ukongeza, ubungqina bubonisa ukuba iintsini ze-CBD eziveliswe kwi-hemp zinokuba nefuthe elihle kwiingxaki ezahlukeneyo zempilo. Iigummies ezinamandla ahlukeneyo kunye nokugxilwa kwe-THC ziyafumaneka kwi-intanethi.
Ugqirha kufuneka adibane naye ngaphambi kokuba asebenzise iimveliso ze-CBD ukuba umntu uthatha iyeza, ukhulelwe/uyancancisa, okanye unesigulo esingaphantsi.
Kuya kufuneka uyazi ukuba i-CBD yikhemikhali ekrakrayo ithetha ukuba iilekese ezininzi zibandakanya iswekile eninzi eyongezelelweyo ukufihla incasa erhabaxa yechiza.
Izibonelelo zentsangu (Imbiza)
Ukutyhubela iminyaka, uphando luvelise iziphumo ezibonisa ukuba intsangu inokuba luncedo ekunyangeni izifo ezithile, kubandakanya umhlaza.Ngokophononongo, intsangu iluncedo ekunyangeni iintlungu ezingapheliyo kunye nokulawula ixhala lentlalontle. Ukongeza, kuye kwaboniswa ukuba i-cannabinoids elawulwa ngomlomo inceda ukunciphisa isicaphucaphu kunye nokuhlanza okuhambelana nechemotherapy. Ezinye izifundo ezincinci ziye zafumanisa ukuba intsangu inokuthi isebenze ekudambiseni iimpawu ezifanayo.
Ukuqukumbela
Impembelelo ye-entourage isathathwa njenge-hypothesis. Kusekho uphononongo oluninzi olufunekayo kwisityalo se-cannabis kunye nokwakheka kweekhemikhali ngaphambi kokumisela uluhlu olupheleleyo lwezinto ezinokubakho zonyango. Hlala udibana nogqirha phambi kokuba uthathe naliphi na iyeza ukuze uqinisekise ukusetyenziswa ngokukhuselekileyo.